Chirlmin Joo studied physics at Seoul National University in Korea. He obtained his PhD in physics under the supervision of Taekjip Ha at the University of Illinois at Urbana-Champaign, USA. He studied a DNA repair process using single-molecule fluorescence. During his PhD study, he advanced single-molecule techniques by innovating new tools including single-molecule multi-color FRET. As a post-doctoral fellow in Narry Kim’s lab at Seoul National University, Korea, he discovered novel proteins in microRNA biogenesis. As a research professor in the same institute, he succeeded reconstitution of functional protein complexes at the single-molecule level.
He has his faculty position at Delft University of Technology in the Netherlands. He applied the single-molecule FRET to mechanistic studies on the target search process of microRNA and CRISPR/Cas9 and the single-molecule pull-down method to the functional studies of protein complexes in microRNA biogenesis and CRISPR memory formation.