Combining holographic optogenetics and computational modeling to illuminate how functional circuitry of the sensory cortex contributes to complex behavior

Developing new analysis methods to uncover the relationships between cortical depth and properties of cortical inhibitory neurons, across species and cortical areas, using publicly-available datasets

Seeking to understand differences between naturally and synthetically evoked neural responses using optogenetics and 2-photon calcium imaging

Designing a custom nanophotonic neural interface to optically stimulate and analyze output of neuronal activity for both in vivo and in vitro optogenetic studies

Focused on exploring societal considerations of Neurobiology and Changing Ecosystems Research, with a specific focus on justice in basic research agendas, the project will work to create a framework that can be used as a method for Neurobiology and Changing Ecosystems researchers to utilize when assessing research directions with inherent scientific, ethical, or societal implications.

Investigate the effects of atmospheric pollutants on plant-pollinator interactions and the processing of floral scents

The Kavli Institute for Particle Astrophysics and Cosmology (KIPAC) pursues a critical test of cold dark matter theory by joining as an institutional member of the Via Project. Via will build twin spectographs for a 5 year survey of the Milky Way.

Determine the role of astrocytes in heat resilience, to better understand how the brain builds resilience to temperature challenges at the cell and molecular level

Investigate the neuronal and circuit principles that underlie functional resilience to temperature in the nematode C. elegans

Applying advanced statistical and machine-learning models to behavioral data from a mouse model of Alzheimer's Disease

Support the Falling Walls Conference for conference activities that explore ethical and societal issues, and public perceptions, of scientific breakthroughs. Ideally, research scientist(s) making breakthrough discoveries, ethicists, and public engagement experts will be included in activities.

Sponsored by Dr. Vladyslav Vyazovskiy in the Physiology, Anatomy and Genetics Department at Oxford University, Kim studies the neuroscience of sleep

Enhance the Multiscale Object-Oriented Simulation Environment (MOOSE) software package and support outreach and training activities to make computational modeling more globally accessible

Enhance DeepLabCut with generative AI (AmadeusGPT) and expand the DeepLabCut AI Residency program

Examine the Supreme Court decision impacting the Chevron deference doctrine, including a focus on impact on scientific expertise at the federal agencies.

Conduct a systemic review of overarching issues facing U.S. science, technology, engineering, and mathematics (STEM) enterprise related to the education, career and workforce development of STEM graduate students and postdoctoral scholars.

Identify the range of programs geared towards training scientists and engineers about the ethical, social, and political dimensions of their work, and provide a better understanding of who provides this kind of training, how it is structured, what kinds of gaps and opportunities there might be, and how a scalable approach might be designed.

Sponsorship for 2024 Advancing Research Impact in Society (ARIS) Summit, April 2 - 5, 2024 in Omaha, Nebraska.

Host a Civic Science Fellow, mentored by Alondra Nelson, Harold F. Linder Professor. Project will seek to build engagement around anticipatory, emerging topics in science and technology, where there is broad potential benefit to civic science approaches.

Sponsored by Kavli Institute for the Physics and Mathematics of the Universe at University of Tokyo, Kalita studies galactic structure

Sponsorship to support costs associated with the Inclusive SciComm meeting in October of 2023.

Host a Civic Science Fellow to focus on “Neuroscience and Society” addressing issues of engaging publics in neuroscience, how publics’ ideas and views might impact research questions, design, and the scientific process, and how these concepts can be built into training of neuroscientists.

Conceptual development of an infrared spectrometer for use with the U.S. Extremely Large Telescope program

Assess the ability of invertebrate species to maintain neuron development and function in response to temperature flux, to address a gap between known ecological effects of climate change and physiological adaptation

Sponsored by Professors Jia Liu and John Silverman at the Kavli Institute for the Physics and Mathematics of the Universe at University of Tokyo, Vovk studies activate galactic nuclei

Sponsored by Kavli Prize Laureate and Professor Conny Aerts at Katholieke Universiteit Leuven, Kliapets studies novel machine learning applications in astrophysics

Sponsored by Kavli Prize Laureate and Professor David Jewett in the Earth, Planetary and Space Sciences Department at the University of California in Los Angeles, Amiri studies astronomy

Develop optogenetic tools to investigate the molecular determinants of mitochondrial metabolism to assess how mitochondiral physiology may modulate brain function

Advance understanding of reaction zone dynamics in carbon nanotube (CNT) synthesis to enable and accelerate scaleable use of sustainable CNTs

Sponsorship of the NAS Standing Committee.

Produce a special issue of the Journal of Science Communication (JCOM) featuring ‘Communicating Discovery Science’ as the core theme, as well as host an international symposium at Stellenbosch University in South Africa on that topic.

Exploration of multifaceted study of materials, including spin-magnetic Kagome materials and biological systems, toward demonstrating broadband quantum transduction

Sponsored by the Kavli Institute for the Physics and Mathematics of the Universe at University of Tokyo, Onoue studies the formation and early growth of supermassive black holes

Develop an open source software application to facilitate converting data into the Neurodata Without Borders (NWB) format using best practices for data and metadata structures

Develop a data pipeline to characterize neuronal population activity and ensemble properties to understand how sensory stimuli and behaviors are representated across brain regions

Advance understanding of molecular pathways associated with learning and memory formation by optical manipulation of neural activity with optical reporters of activity and synaptic strength, as an outcome of "Scialog: Molecular Basis of Cognition"

Develop a software extension to convert marmoset intracellular electrophysiology datasets into a data standard suitable for public access

Develop automated extraction tool to retrieve stored metadata as part of a pipeline to standardize a multi-modal dataset

Develop a software extension to manage data and metadata from deep brain stimulation experiments

Develop a software extension to integrate holographic photostimulation data into a data standard and integrate into two-photon image analysis packages

An outcome of the Scialog, "Signatures of Life in the Universe"

Investigate how cephalopods cope with environmental changes, such as low oxygen availability (hypoxia), to advance studies in RNA editing and neural adaptation

Support for a postdoctoral fellowship program associated with Harvard's Origins of Life Initiative and the larger Origins Federation (Harvard, U Chicago, Cambridge, ETH Zurich)

Engage researchers to write about frontiers in science and to probe the societal challenges and opportunities the emerging research could introduce.

Develop the first self-consistent mechanistically-informed model of abiotic sulfur cycling by integrating laboratory experiments and modeling, as an outcome of the Scialog(R): Signatures of Life in the Universe

Examine public attitudes and understanding of select areas of basic science and analyze the existing literature on how the public thinks about the current and potential applications of emerging basic science.

Sponsorship to support 2023 and 2025 Public Communication of Science and Technology (PCST) meetings.

This project seeks to understand how discourse around bioethical aspects of human brain models interact with diverse epistemic belief systems to influence public attitudes around moral values towards neuroscience.

Support for trainings that empowers scientists to bridge divides through meaningful conversations, moving from correction to connection.

Provide infrastructure and resources to support the Leaders in Science and Technology Network (LISTEN) network leaders in their efforts to advance their shared priorities of Network members.

Develop custom hardware and software to enable microscopy of 3D voltage imaging in deep-brain neural circuits

Extend an open source software toolbox used for songbird neurophysiology analysis, BirdSong, to support Neurodata Without Borders (NWB)

Create a pipeline to convert single-unit data from working memory tasks into the Neurodata Without Borders (NWB) data standard

Combine imaging-based single-cell transcriptomics and miniature 2-photon microscopy to measure gene expression impact on neural clusters and cell types in neural circuits that control social behavior in mice

Develop and apply innovations in metamaterial design to enhance performance of fluorescence photometry

Establish a data standard for existing brain-computer interface frameworks and datasets

Expand the Neurodata Without Borders (NWB) ecosytem to include the open source 4D neuron tracing software package Dynamo

Create a Neurodata Without Borders (NWB) database to share data for optogenetic perturbation of recurrent cortical connections

Develop an open source computational pipeline for constructing functional neural networks, in collaboration with Yi-Yun Ho (Massachusetts Institute of Technology)

Combine and analyze publicly available data to understand principles that shape neuronal activity across species, and gain insight into population dynamics of complex neuronal circuits

Integrate neurophysiology and network analysis methods to study brain function during a novel memory task, in collaboration with Dr. Lucas Pinto at Northwestern University and Dr. Daniel Burnston at Tulane University as an outcome of "Scialog: Molecular Basis of Cognition"

Develop and apply molecular tools to analyze neural dynamics, gene expression and behavior during a novel rodent learning task, in collaboration with Dr. Antonio Fernandez-Ruiz at Cornell University as an outcome of "Scialog: Molecular Basis of Cognition"

Develop a novel method to track real-time, physiological arousal states to inform mechanisms of Parkinson's disease in a rodent model

Develop a magnetic force microsope to measure the magnitude and dynamics of activity-dependent neuronal magnetic fields

Advance functionality and accessibility of ClearMap software, to analyze large volumetric data from the brain

Develop tools and open standards to create advanced, multiscale models of neuronal cells through the COmputational Modeling in Biology NEtwork (COMBINE) initiative

Develop an open C/C++ API for data acquisition for the Neurodata Without Borders (NWB) data standard

Investigate the influence of environmental context and valence on neural responses in the basolateral amygdala

Develop new tools to study biophysical perturbations in neuronal cell properties, to explore adaptability of neural systems

Support for the Science Society Engagement Network, a cross-organizational network that supports scientific societies in their efforts to equip and encourage scientists to effectively engage with diverse public audiences.

Develop a computational model to uncover the variability of neural circuits across experimental trials, tasks and conditions, and apply this framework to publicly-available datasets

Sponsorship to suppor the Falling Walls 2022 Conference.

Support for a full-time Engagement Officer at the MIT Kavli Institute (MKI) who will coordinate the outreach activities of individual investigators into a coherent MKI-wide public-facing program on Astrophysics and Space Exploration.

Establish the Kavli Centre for Ethics, Science and the Public at Cambridge to advance education in science and the understanding of ethical implications born from scientific discovery for the benefit of the public by delivering a vision of innovative public engagement methodologies across a broad spectrum of scientific domains.

Establish the Kavli Center for Ethics, Science and the Public at Berkeley to provide an inclusive, multidisciplinary framework for understanding the ethical implications of science and technology, guiding the development of policy concerning anticipated and actual scientific advances and helping to ensure that those advancements are answerable to fundamental human interests.

Support for the SciComm Trainer network

Convene a meeting on the anniversary of Vannevar Bush's "Science, the Endless Frontier" report, to examine the "Next 75 Years" of science.

Publish a series of articles written by diverse perspectives on opportunities in science policy in the theme of "The Next 75 Years of Science and Innovation Policy."

Support for a full-time staff person to develop, lead, and grow engagement activities at Kavli Institute for Particle Astrphysics and Cosmology (KIPAC).

A creation of a global report synthesizing the state of pure science around the world, with associated events.

Host a Civic Science Fellow to explore how to better help varied audiences engage with science, including the impact of scientific advances on society and ethical issues surrounding those advances. Work focused on learning more about digital, student and educator audiences.

Support for the Society Civic Science Initiative (SCSI), a cross-organizational collective impact network supports scientists’ public and civic engagement efforts.

Sponsorship for the 2021 Communicating Astronomy to the Public conference.

Support a communication training pilot to build and deliver a dedicated training module, allowing astronomers around the world to learn effective methodologies for public engagement and shift astronomers’ approaches towards effective engagement and helping scientists better articulate their objectives for delivering public engagement activities.

Lead a literature review and analysis about the how basic science is covered in literature about science communication and engagement.

Create a summary of the scope and scale of existing research about science communication and public engagement that could provide guidance to science communicators working ‘basic’ or ‘discovery’ scientific research.

Support to develop a national strategy for science engagement which provides opportunities for everyone to participate in, use, learn from, and guide science. Focus on investments in U.S. R&D that can be paired with commensurate federal support for science engagement that increases public access to and participation in the scientific enterprise.

Produce a landscape report from research and interviews to better understand if and how various scientific issues with ethical implications have engaged the public.

These ongoing evening lectures feature a moderated discussion with Kavli Prize Laureates regarding their science and career journey.