Funded Work

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Decoding Aging Neurons

Andrew Holbrook

Applying advanced statistical and machine-learning models to behavioral data from a mouse model of Alzheimer's Disease

Field
  • Neuroscience
Funding Period
  • 2024-2026
Program
  • Observe and Measure the Mind
Institution
  • University of California, Los Angeles
Collaborators
  • Karen Toffler Charitable Trust
  • Cure Alzheimer's Fund

Uncovering the Metabolic Control of Neuronal Communication

Jaime de Juan-Sanz, Pavan Ramdya

Develop optogenetic tools to investigate the molecular determinants of mitochondrial metabolism to assess how mitochondiral physiology may modulate brain function

Field
  • Neuroscience
Funding Period
  • 2023-2025
Program
  • Kavli Exploration Award
  • Observe and Measure the Mind
Institution
  • Paris Brain Institute
  • Swiss Federal Institute of Technology Lausanne

Metamaterial Design for Lenses

Yevgenia Kozorovitskiy, Abdoulaye Ndao

Develop and apply innovations in metamaterial design to enhance performance of fluorescence photometry

Field
  • Neuroscience
Funding Period
  • 2022
Program
  • Kavli Exploration Award
  • Sculpted Light
  • Observe and Measure the Mind
Institution
  • Northwestern University
  • Boston University

Optical Control to Study Parkinson's Disease

Luis Carrillo-Reid, Jose Rodríguez-Romaguera

Develop a novel method to track real-time, physiological arousal states to inform mechanisms of Parkinson's disease in a rodent model

Field
  • Neuroscience
Funding Period
  • 2022
Program
  • Kavli Exploration Award
  • Sculpted Light
  • Observe and Measure the Mind
Institution
  • National Autonomous University of Mexico
  • University of North Carolina at Chapel Hill

Computational Microscopy for High-Speed Voltage Imaging

Nicolas Pégard

Develop custom hardware and software to enable microscopy of 3D voltage imaging in deep-brain neural circuits

Field
  • Neuroscience
Funding Period
  • 2022
Program
  • Kavli Exploration Award
  • Sculpted Light
  • Observe and Measure the Mind
Institution
  • University of North Carolina at Chapel Hill

Multiplex Imaging: Neural Activity and Spatial Transcriptomics

Changwoo Seo, Weijian Zong

Combine imaging-based single-cell transcriptomics and miniature 2-photon microscopy to measure gene expression impact on neural clusters and cell types in neural circuits that control social behavior in mice

Field
  • Neuroscience
Funding Period
  • 2022
Program
  • Kavli Exploration Award
  • Sculpted Light
  • Observe and Measure the Mind
Institution
  • Harvard University
  • Kavli Institute for Systems Neuroscience (Norwegian University of Science and Technology)

Measuring Magnetophysiology

David Hunt, Mladen Barbic

Develop a magnetic force microsope to measure the magnitude and dynamics of activity-dependent neuronal magnetic fields

Field
  • Neuroscience
Funding Period
  • 2022
Program
  • Kavli Exploration Award
  • Observe and Measure the Mind
Institution
  • Cedars-Sinai Medical Center
  • NYU Langone Health