Seeking to understand differences between naturally and synthetically evoked neural responses using optogenetics and 2-photon calcium imaging

Designing a custom nanophotonic neural interface to optically stimulate and analyze output of neuronal activity for both in vivo and in vitro optogenetic studies

Combining holographic optogenetics and computational modeling to illuminate how functional circuitry of the sensory cortex contributes to complex behavior

Applying advanced statistical and machine-learning models to behavioral data from a mouse model of Alzheimer's Disease

Develop optogenetic tools to investigate the molecular determinants of mitochondrial metabolism to assess how mitochondiral physiology may modulate brain function

Develop and apply innovations in metamaterial design to enhance performance of fluorescence photometry

Develop a novel method to track real-time, physiological arousal states to inform mechanisms of Parkinson's disease in a rodent model

Develop custom hardware and software to enable microscopy of 3D voltage imaging in deep-brain neural circuits

Combine imaging-based single-cell transcriptomics and miniature 2-photon microscopy to measure gene expression impact on neural clusters and cell types in neural circuits that control social behavior in mice

Develop a magnetic force microsope to measure the magnitude and dynamics of activity-dependent neuronal magnetic fields